Stimulant Medication Effects on ADHD

Posner Lab

How Do Stimulant Medications Treat Symptoms of ADHD?

 

What Is ADHD?

Attention-deficit/hyperactivity disorder (ADHD) is one of the most common childhood behavioral disorders, with symptoms that often continue into adolescence and adulthood. Behaviors associated with ADHD include inattention, hyperactivity, impulsivity, and emotional lability.
 

Research Program Overview

Stimulant medications have shown to effectively treat symptoms of ADHD, though not much is known about how these stimulants work. By using neuroimaging, this study aims to understand the mechanisms by which an approved stimulant medication, lisdexafetamine (also known as LDEX or Vyvanse), reduces emotional lability and other ADHD symptoms. By participating in this study, your child will receive the following at no cost:

  • Psychiatric evaluation
  • MRI scan
  • 1 month of free treatment (only for children with ADHD)
 

Who Is Eligible to Participate?

Participants must:

  • Be between 6 and 25 years old
  • Be diagnosed with ADHD or not diagnosed with any psychiatric disorders (healthy controls)
  • Not be taking any current psychiatric medications or participating in psychotherapy
 

Study Procedures

Healthy control Participants:

  • Psychiatric evaluation
  • MRI scan
  • 12 weeks of controlled treatment with a stimulant medication or placebo (sugar pill)

Participants diagnosed with ADHD:

  • Psychiatric evaluations before and after treatment
  • MRI scans before and after treatment
  • 12 weeks of controlled treatment with a stimulant medication or placebo (sugar pill)
  • 1 month of free treatment at the end of the study
 

Compensation

Study testing, medication, and evaluations are provided at no cost to you. You and your child will receive compensation for participation in the study, in addition to reimbursement for transportation, as follows:

  • The maximum amount of compensation child ADHD participants can earn is $300. The maximum amount of compensation their parents can earn is $600.
  • The maximum amount of compensation child healthy control participants can earn is $175.
 

Interested in Learning More?

Contact us!

Jonathan Posner
Phone: 646-774-5863
Email: posnerj@nyspi.columbia.edu